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Cell culture Greiner Bio-One 3D cell culturing - Magnetic suspensions and bioprinting 3D cell culture - Spheroids - Organoids : M3D Greiner Bio-One Kit
3D cell culture - Spheroids - Organoids : M3D Greiner Bio-One Kit
Description
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System for 3D cell culture thanks to the transient magnetization of cells that naturally attach to the NanoShuttle-PL magnetic beads.
Thanks to the magnetic force, the cells are ready for either magnetic levitation or spheroid printing, to form 3D in vitro representation models.
  • in vitro reproduction of the native tissue environment
  • Versatile system compatible with all cell types even in co-culture
  • 3D model formation in a few hours after incubation with magnetic beads
  • Allows cell co-culture
  • No impact of the magnetized beads on the cells (proliferation, viability, phenotype ...)
  • Centered positioning of the spheroids
  • No specialized equipment, no media, no artificial substrate
  • Easy to handle, no sample loss
Source : Greiner Bio-One
Magnetic levitation
Spheroid printing
Magnetic ring printing and imaging system
Magnetic NanoShuttle-PL
Accessory
Transiently and non-invasively magnetized cells are placed in a Cell-Repellent plate. A magnet placed above the plate attracts the cells to the air/medium interface. Magnetic forces bundle the cells together, favouring intercellular interactions at the origin of the extracellular matrix synthesis.
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Transiently and non-invasively magnetized cells are placed in a plate and a magnetic holder will be positioned underneath that plate, keeping the cells at the bottom of the well. In a few minutes or even hours, the plate containing the spheroids can be removed from the magnetic holder and cultured over the long term.
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Based on the 3D magnetic Spheroid printing, transiently and non-invasively magnetized cells thanks to Nanoshuttle-PL beads are positioned in a ring shape mimicking certain in-vivo patterns and their functions (ex. contraction).
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  • Nano-particles assembly (50 nm diameter), does not bind any specific receptors, works with all cell types - attaches to the plasma membrane electrostatically
  • Consists of biocompatible gold, iron oxide and Poly-L-Lysine
  • No effects on proliferation, viability, metablism, oxydative stress, phenotype
  • Does not disturb experimental techniques such as immunohistological labelling, fluorescence detection, HR microscopy, Western Blot, PCR/qPCR ...
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Magnetic tool for the individual manipulation of formed spheroids
No item has been found in Dominique DUTSCHER catalog, or in your market conditions
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