Artificial tumours® (3D cultures) from tumour cell lines widely used in oncology
• More closely mimics the microenvironment of avascular tumours in vivo than 2D cultures
• Increasingly involved in the development of medicines
• Ideal study solution for aggressive triple-negative breast cancer
The Opti3D kit® includes artificial tumours® produced in OptiPASS® culture medium in 96-well microplates (one tumour per well)
• Transport in anoxia and at 4 °C for dormancy until use (alternative to freezing)
• Each microplate includes 100 ml of suitable culture medium (OptiPASS® OPTI03) for in vitro testing
Benefits
• Direct use of tumours after deconditioning
• Reproducible tumour size and morphology
• Guaranteed: less than 10% variation in size within and between microplates
• Once deconditioned, resumption of tumour growth for a minimum of 10 days
• Available for triple-negative breast cancer, very aggressive subtype: MDA-MB-231 line, SUM1315 line
• Ideal for screening, toxicity testing or basic research into mechanisms of interest
